Greetings iMedDo newsletter subscribers. This month I reveal the results of my meditation on the mineral magnesium which I found out is extremely mighty. To talk about Magnesium, I want you all my dear readers to pretend you are witches & wizards at Hogwarts in Harry Potter and here is the course syllabus:
MAGNESIUM MAGE 101
In this class we will be learning the essential wizardry knowledge of how to start a fire, make a loud bang and a bright light with magnesium alchemy, must have knowledge for any Magi. Magnesium alchemy is earth metal that can be used for the fire & water of life necessary for all creatures both magical & muggles. In lab we will be recreating dragon fire and dragon fire resistant crucibles with magnesium as well as using magnesium magic to break bones and magnesium medicine to mend them.
Would you take the class? lol If so then read on!
WHAT IS MAGNESIUM?
Magnesium is the 12th element on the periodic table. It’s predominantly found in nature in the Mg2+ oxidation state and can be made into Mg(0) metal form which is highly flammable but safe for storage as forms an oxidized passivization layer. Magnesium is not a heavy metal (it’s a light metal in the heavy vs light non-medicinal paradigm) & magnesium is not a heavy metal (not a toxic metal) in the medicinal paradigm either as maganesium in ionic form is a critial mineral nutrient for all known life.
MAGNESIUM FOR CAMPING
Did you known you can get a magnesium fire starter which can be used to start a fire even in damp conditions. Magnesium metal bar is scraped with a knife or small saw to form highly flammable magnesium flakes which are useful to get the fire going. So useful!
MAGNESIUM FOR FIREWORKS
Did you know that magnesium is used in fireworks to make white light and to increase overall intensity of the brightness. Hope you all had a great 4th of July weekend recently. We saw 4 firework shows in 4 days July 1,2,3 & 4th!!!
MAGNESIUM MAGI MAGNATES
Magnesium has probably been used since the dawn of time by MAGI for magical effects like flash bang powder and more recently for photography flashes and hollywood special effects. The word magnesium appears to come from ancient Greece named after the area called Magnesia (Thessaly Area) where there was an tribe called the Magnetes.
I suspect that Magnesium special effects were used by the priests/priestesses for special effects (white lights and bangs) for the temple of Artemis, and likely magnesium oxide white paint was used in temple art.
Words including Magnesium, Manganese, Magnetic for sure and likely many others (Magnificent, Magnus, Magi, Magus, Mage, iMage, iMagination etc) may have similar etymology.
MAGNESIUM MILITARY APPLICATIONS
Magnesium can be used to make explosive detonators & for making potent firebombs that cannot be put out with water or even if you deprive them of oxygen will continue burning in nitrogen atmosphere. Magnesium firebombs were deployed in WW2 and required dousing in sand to put out as they had to be deprived of atmosphere both oxygen and nitrogen to get them to stop burning.
MAGNESIUM NON-MEDICINAL CIVILIAN APPLICATIONS
I saw so many uses for magnesium that it was overwhelming, here are a few of the non-medical ones that jumped out at me: Magnesium carbonate is known as chalk & is useful in athletics like rock climbing, weight lifting and gymnastics. Magnesium used in construction to make bricks stick together or non-gypsum drywall alternative popular in China where large magnesium stores located. Magnesium though flammable in metallic form can be crafted in to flame retardant and flame resistant materials and magnesium is used in making crucibles for heating other metals and chemicals.
I just went hang-gliding for the first time in my life something I always wanted to try. While researching magnesium for this episode I found out that magnesium can be alloyed with aluminum for an even lighter metal composite for aircraft, and very likely my hang-glider had magnesium in its frame that kept me up in the air. Great fun!
Instead of magnesium metal form, in biology it is magnesium ion form (Mg2+) that is relevant. Why is it relevant is a question I think I can answer, it’s based on the fact that Magnesium ions are the second most abundant ion present in sea water (after sodium Na+ ions) and magnesium is the third most abundant element in sea water. So if you believe that early life evolved in the ocean which it appears that it did, then it only makes sense that such early life would need to figure out a way to deal with Magnesium ions. The early membrane enclosed life at a minimum would need to find a way to excrete magnesium ions since they would be always entering the early cell from concentration gradient of high magnesium in sea water and lower magnesium ion concentration inside the early life of membrane enclosed organelles. Early in evolution life was able to use the energy molecule ATP (adenosine triphosphate) to pump molecules against a concentration gradient via what we now call “active transport” as opposed to molecules diffusing down a concentration gradient energy free called “passive transport”. Magnesium ion is able to associate with a phosphate group and thus stabilize ATP molecules and thus using magnesium ions appears to have evolved very early possibly at the very git go of early life evolution and likely immediately became one of the first signaling molecules along to signal low energy if an ATP molecule is used up and Mg2+ is released. It is thought that there is a Mg2+ ion for every ATP molecule in the body so you can imagine that a deficiency of Mg2+ (which would never happen in the ocean as is abundant there) would result in disruption of energy pathways of active transport that involve ATP and also possibly regulation of phosphates and adenosine likely disrupting Adenine nucleotide synthesis necessary for both early RNA and DNA of early life. Somehow in evolution, sodium Na+ the most abundant ion in sea water became coupled with potassium K+ for signaling and in a similar way perhaps magnesium Mg2+ became coupled with calcium Ca2+ for signaling. I’m just spitballing here but it looks to me like Magnesium was used for the energy necessary to do things like remodel calcium in coral and then millions if not a billion+ years later, we as humans is like we have coral inside our body (our bones) that still use a similar magnesium & calcium evolved processes that originally came from sea water evolution. But whereas in the ocean magnesium is abundant, for life outside the ocean, magnesium is more scarce so systems to keep ions magnesium and calcium in became important.
MAGNESIUM BIOCHEMISTRY: SPARTAN PROTEINS
There are 300 known proteins in the human body that use magnesium. These 300 “Spartan” proteins are mostly hardcore ATP energy molecule binding proteins.
Muscles proteins reset/relax in the presence of magnesium as it brings in an ATP molecule prepping muscle for a future contraction relaxed but ready! Famous health comedian body builder JP Sears I noticed has a magnesium supplement he promotes at end of each of his episodes presumably for muscle building.
Studies show that magnesium helps build bone density so not just relaxed muscles, also helps body make stronger bones to hold those big muscles.
MAGNESIUM KUNG FU
Kung Fu students repeatedly whacking their bones against a brick or other resistance to strengthen their bone hardness could maybe reduce their training time if using magnesium supplements. Shaolin monks are notorious for having rock hard heads from extensive concussive training giving them dangerous headbutt attacks and immunity to elbow to the head strikes from untrained fighters. Diamond Body, Knife Hands, and many techniques of the highly trained higher rely on hardened bones not just agility and muscle strength, and am curious see if there are any studies about using magnesium for fighter training.
Besides diet & salt, magnesium is used in medicine in antacids, in laxatives, in health supplements.
Magnesium salt (Epsom’s salt which is magnesium sulphate) is particularly useful for detox as you can dissolve the salt in water and soak in it or soak your feet in it to do a heavy metal pull out of your skin and I routinely recommend this a synergistic way to detox faster when using iMedDo Detox system.
Additionally soaking in magnesium salt is good for sore muscles. Another way people use magnesium for sore muscles is to use a magnesium oil that they rub on the skin.
Magnesium hydroxide is used in some antacids (Rolaids but not Tums) & is also used in laxative known as Milk of Magnesia.
Eating most magnesium salts or most any salts in too high a quality will result in a laxative effect as the undissolved salts in the intestines will pull water from the body resulting in water bowel movement.
Besides magnesium salt soak or magnesium oil rub, nowadays you can also get a number of different edible magnesium pills. Of these avoid magnesium oxide as is not very bioavailable. I’ve heard magnesium lysinate is good from a person (who wants to remain anonymous) who had been on magnesium oxide to no effect then got a more bioavailable form with the magnesium lysinate supplement and could feel muscles immediately relaxing. People also say that their magnesium supplements help them sleep better, and relaxing your muscles before bed makes sense to me.
Magnesium is thought to be involved with helping people with hypertension & cardiovascular disease, type 2 diabetes, osteoporosis and migrane headaches.
Sometimes when people are taking magnesium for hypertension (high blood pressure) it doesn’t work but then they take iodine instead the high blood pressure immediately goes down, so if you have hypertension and your magnesium supplement not work, first check to make sure is not magnesium oxide get a good one, and if still not working, try iMedDo detox system. High blood pressure when iodine deficient is your brain trying to send more iodine to itself and when it gets enough iodine if that was the problem the blood pressure will go back down almost immediately within 30 min of getting the iodine.
I’m very interested in learning more about how magnesium is beneficial to the heart to help with heart healing after vaccinosis as that’s a problem many people tricked into poisoning themselves by Pfizer and other shameful Big Pharma companies are dealing with at the moment.
I’m familiar now that magnesium supplementation is beneficial for people with diabetes thanks to DrPop’s book on Diabetes recently read. Magnesium as I said is important for ATP energy pathways and so is no surprise is involved in insulin/sugar/energy pathways.
I’ve been familiar with people taking magnesium for osteoporosis (loss of bone density) for a long time. Like I say they usually tell me they taking magnesium and it not working and I recommend they take iMedDo detox system to flush out halogen and heavy metal toxins blocking their calcium/magnesium balance in their body.
I wasn’t aware until doing research for this article that some people use magnesium for migranes, but it seems if you get low in magnesium it will give you a migrane that not being deficient in magnesium will remedy. Try that first but if still migrane get some NeuGold colloidal gold for the migrane. Do 3 drops NeuGold under tongue as needed. Colloidal gold works for migrane because it detoxes whatever is causing inflammation in brain (gold is anti-inflammatory in the brain and nerves).
MORE THINGS I WANT YOU TO KNOW
Magnesium is medicine because it is used for hundreds of proteins in the body and it is a signaling molecule related to energy molecule ATP.
Besides its use in energy metabolism is used in protein synthesis, and contributes to proper brain, bone, muscle, and heart function.
Magnesium pathways likely evolved very early in creation of early life on planet earth because of high concentration of magnesium ions in sea water.
Magnesium evolved to be intricately related to calcium signaling in the body and all the normal things that screw up calcium signaling (fluoride, low vitamin D, heavy metals etc) also screw up the magnesium pathways which is why iMedDo Detox is very useful for restoring balance of magnesium in the body.
Magnesium health supplements are most well known used for soothing muscles, but have many other medical uses such as sleep, diabetes, osteoporosis, cardiovascular health, hypertension and maybe even migrane.
Most commonly I run into people at fairs who are using magnesium for muscle cramps and osteoporosis.
I’m really on the fence about taking oral magnesium as I like Epsom salt bath and magnesium oil instead but if you do use oral magnesium don’t recommend magnesium oxide for as not bioavailable and don’t eat magnesium sulphate or magnesium hydroxide as is a laxative. Try magnesium lysinate or some other form where magnesium ion is more bioavailable.
Magnesium and Calcium are in a balance in the body that is controlled by iodine. If you are low calcium instead of taking calcium health supplements you need to try iodine and/or magnesium supplements instead. When you have fluoride in your body it binds insolubly to calcium disrupting calcium signaling pathways that disrupt magnesium signaling pathways.
It’s hard to measure your magnesium levels as your blood levels of magnesium are not indicative of amount of magnesium in your body since most is in the bones and the levels change when you eat & increase when you exercise.
Magnesium is or should be abundant in your diet so likely if you are experience symptoms of low magnesium you likely have enough in your body it’s just that the pathway is blocked somewhere. The main things iMedDo Detox system unblocks are fluoride & heavy metals which when detoxed and when iodine replenished should result in restoration of proper calcium/magnesium balance in the body.
If you calcium levels are off too high or too low, your magnesium levels correspondingly will be off. People want to take more calcium or take more magnesium to fix frequently it doesn’t work because what they really need it more iodine.
Counterintuitively when you have low calcium you should not take more calcium. Instead you should take magnesium and iodine (and whenever you take iodine use NeuIodine in system with NeuSilver & NeuGold).
Also if you have high calcium you should take more magnesium and iodine.
Many more people benefit from taking a magnesium health supplement than a calcium health supplement.
Recommended dosage for magnesium is 200-400 mg/day depending on age & gender.
There is not much magnesium in the Power Source One Multi-vitamin that I’ve been recommending because it is expected that you should either be getting enough magnesium in your diet.
I don’t do magnesium supplements as I get enough magnesium in my diet. Primarily in nuts in particular for me in peanuts and in chocolate =). Some common high magnesium foods include spinach , dairy, avocados, pumpkin seeds, spirulina, nori(algae), pink salt, dark chocolate, wild caught fish, & sprouts, nuts (almonds, peanuts, pistachio nuts), and bananas.
Magnesium is widely distributed in plant and animal foods and in beverages. Green leafy vegetables, such as spinach, legumes, nuts, seeds, and whole grains, are good sources In general, foods containing dietary fiber provide magnesium. Magnesium is also added to some breakfast cereals and other fortified foods. https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/
You shouldn’t need a magnesium health supplement under normal circumstances because you should get enough magnesium in your diet. However for for certain people like with diabetes, alcoholism, or dysregulation in calcium pathways (bone spurs or osteoporosis) taking a magnesium supplement could be a good idea for them.
However, I normally just recommend people soak in Epsom salt (magnesium sulphate) as they can get some magnesium and detox at the same time.
I have some left over Karma rub magnesium oil from Australia that I traded for at a fair if anyone needs contact me, and I’ll ship with your next iMedDo order.
My take is that most of you have plenty of magnesium in your body already but if you are having symptoms of low magnesium and/or calcium dysregulation then is also critical to also take iodine in particular NeuIodine with iMedDo Detox system as it will flush out fluoride and heavy metal disrupters of the magnesium/calcium balance in your body restoring homeostasis.
However, doing this newsletter has made me uncertain about magnesium. What if I’m wrong and a lot more people need magnesium than I realize? Magnesium is a multifaceted mandala a lot more complicate and involved in a lot of biochemical pathways than I realized. Although in supposedly used in only 300 as opposed to zinc being in 3000 proteins, magnesium seems to be in more ancient pathways as evolved very early to be required for energy signaling with ATP, phosphate and calcium and A amino acid synthesis so seems mission critical to make sure you have enough.
If you even think you might be low in magnesium just take some! Or better yet eat a food high in magnesium to get it in your diet. If you feel better immediately then yeah you were low! For me my go to magnesium snack is peanuts and chocolate =)
APPENDIX: MAGNESIUM FACTS & COMMENTS
Source: SRC NIH MG FACT SHEET
Adult body contains about 25 g of magnesium with 50-60% of it in the bones and the rest in soft tissues. Less than 1% of total magnesium is in blood serum, and these levels kept in tight control. Hypomagnesemia is defined as a serum magnesium level less than 0.75 mmol/L . Magnesium homeostasis is largely controlled by the kidney, which typically excretes about 120 mg magnesium into the urine each day . Urinary excretion is reduced when magnesium status is low .
***If you pee out 120 mg Mg2+ a day you probably need to replace at least that much in the diet!
Approximately 30% to 40% of the dietary magnesium consumed is typically absorbed by the body [2,9].
*** If you need to absorb 120 mg Mg2+ a day but only absorb 35% of what you eat then doing the math you need 343 mg Mg2+ a day in your diet to absorb 120 mg! ***
Magnesium also plays a role in the active transport of calcium and potassium ions across cell membranes, a process that is important to nerve impulse conduction, muscle contraction, and normal heart rhythm .
HIGH ZINC CAN DISRUPT MAGNESIUM ABSORPTION!
One study found that very high doses of zinc from supplements (142 mg/day) can interfere with magnesium absorption and disrupt the magnesium balance in the body .
GROUPS AT RISK FOR MAGNESIUM DEFICIENCY:
Type 2 diabetes, Crohn’s & celiac disease, Alcoholism, Older Adults
People with type 2 diabetes
Magnesium deficits and increased urinary magnesium excretion can occur in people with insulin resistance and/or type 2 diabetes [25,26]. The magnesium loss appears to be secondary to higher concentrations of glucose in the kidney that increase urine output .
People with gastrointestinal diseases
The chronic diarrhea and fat malabsorption resulting from Crohn’s disease, gluten-sensitive enteropathy (celiac disease), and regional enteritis can lead to magnesium depletion over time . Resection or bypass of the small intestine, especially the ileum, typically leads to malabsorption and magnesium loss .
People with alcohol dependence
Magnesium deficiency is common in people with chronic alcoholism . In these individuals, poor dietary intake and nutritional status; gastrointestinal problems, including vomiting, diarrhea, and steatorrhea (fatty stools) resulting from pancreatitis; renal dysfunction with excess excretion of magnesium into the urine; phosphate depletion; vitamin D deficiency; acute alcoholic ketoacidosis; and hyperaldosteronism secondary to liver disease can all contribute to decreased magnesium status [2,27].
**Alcoholics pee out too much Mg2+ from high kidney glucose**.
Older adults have lower dietary intakes of magnesium than younger adults [21,28]. In addition, magnesium absorption from the gut decreases and renal magnesium excretion increases with age . Older adults are also more likely to have chronic diseases or take medications that alter magnesium status, which can increase their risk of magnesium depletion [1,30].
Symptomatic magnesium deficiency due to low dietary intake in otherwise-healthy people is uncommon because the kidneys limit urinary excretion of this mineral . However, habitually low intakes or excessive losses of magnesium due to certain health conditions, chronic alcoholism, and/or the use of certain medications can lead to magnesium deficiency.
Early signs of magnesium deficiency include loss of appetite, nausea, vomiting, fatigue, and weakness. As magnesium deficiency worsens, numbness, tingling, muscle contractions and cramps, seizures, personality changes, abnormal heart rhythms, and coronary spasms can occur [1,2]. Severe magnesium deficiency can result in hypocalcemia or hypokalemia (low serum calcium or potassium levels, respectively) because mineral homeostasis is disrupted .
** magnesium effect to help some people with migranes could be an anti-inflammatory antioxidant effect of body being able to make glutathione again which maybe it was short on since low magnesium?**
Magnesium is involved in bone formation and influences the activities of osteoblasts and osteoclasts .
MAGNESIUM THYROID & BONES! IODINE & MAGNESIUM & CALCIUM BALANCE
Magnesium also affects the concentrations of both parathyroid hormone and the active form of vitamin D, which are major regulators of bone homeostasis.
MORE MAGNESIUM MORE BONE DENSITY
Several population-based studies have found positive associations between magnesium intake and bone mineral density in both men and women .
MAGNESIUM DEFICIENCY RISK FACTOR FOR OSTEOPOROSIS
These and other findings indicate that magnesium deficiency might be a risk factor for osteoporosis .
MAGNESIUM HELPS WITH MIGRANES
Magnesium deficiency is related to factors that promote headaches, including neurotransmitter release and vasoconstriction . People who experience migraine headaches have lower levels of serum and tissue magnesium than those who do not.
However, research on the use of magnesium supplements to prevent or reduce symptoms of migraine headaches is limited. Three of four small, short-term, placebo-controlled trials found modest reductions in the frequency of migraines in patients given up to 600 mg/day magnesium . The authors of a review on migraine prophylaxis suggested that taking 300 mg magnesium twice a day, either alone or in combination with medication, can prevent migraines .
In their evidence-based guideline update, the American Academy of Neurology and the American Headache Society concluded that magnesium therapy is “probably effective” for migraine prevention . Because the typical dose of magnesium used for migraine prevention exceeds the UL, this treatment should be used only under the direction and supervision of a healthcare provider.
TOO MUCH MAGNESIUM?
Too much magnesium from food does not pose a health risk in healthy individuals because the kidneys eliminate excess amounts in the urine . However, high doses of magnesium from dietary supplements or medications often result in diarrhea that can be accompanied by nausea and abdominal cramping . Forms of magnesium most commonly reported to cause diarrhea include magnesium carbonate, chloride, gluconate, and oxide . The diarrhea and laxative effects of magnesium salts are due to the osmotic activity of unabsorbed salts in the intestine and colon and the stimulation of gastric motility .
TOO MUCH MAGNESIUM RESULTS IN LOW BLOOD PRESSURE HYPOTENSION
Very large doses of magnesium-containing laxatives and antacids (typically providing more than 5,000 mg/day magnesium) have been associated with magnesium toxicity , including fatal hypermagnesemia in a 28-month-old boy  and an elderly man . Symptoms of magnesium toxicity, which usually develop after serum concentrations exceed 1.74–2.61 mmol/L, can include hypotension, nausea, vomiting, facial flushing, retention of urine, ileus, depression, and lethargy before progressing to muscle weakness, difficulty breathing, extreme hypotension, irregular heartbeat, and cardiac arrest . The risk of magnesium toxicity increases with impaired renal function or kidney failure because the ability to remove excess magnesium is reduced or lost [1,29].
Magnesium can form insoluble complexes with tetracyclines, such as demeclocycline (Declomycin®) and doxycycline (Vibramycin®), as well as quinolone antibiotics, such as ciprofloxacin (Cipro®) and levofloxacin (Levaquin®). These antibiotics should be taken at least 2 hours before or 4–6 hours after a magnesium-containing supplement
** detox garbage antibiotics that disrupt magnesium and use colloidal silver antibiotic instead.**
Parathyroid hormone (PTH), also called parathormone or parathyrin, is a peptide hormone secreted by the parathyroid glands that regulates the serum calcium concentration [which will affect magnesium concentration] through its effects on bone, kidney, and intestine
BONE REMODELING NEEDS MAGNESIUM & CALCIUM & PARATHYROID HORMONE
PTH influences bone remodeling, which is an ongoing process in which bone tissue is alternately resorbed and rebuilt over time.
PTH VS THYRO-CALCITONIN
It is a polypeptide containing 84 amino acids, which is a prohormone. It has a molecular mass around 9500 Da. Its action is opposed by the hormone calcitonin.Historically calcitonin has also been called thyrocalcitonin
It is functionally an antagonist with PTH and Vitamin D3.
More specifically, calcitonin lowers blood Ca2+ levels in two ways:
Major effect: Inhibits osteoclast activity in bones, which break down the bone Minor effect: Inhibits renal tubular cell reabsorption of Ca2+ and phosphate, allowing them to be excreted in the urine
The calcitonin receptor is a G protein-coupled receptor localized to osteoclasts as well kidney and brain cells. It is coupled to a Gsα subunit, thus stimulating cAMP production by adenylate cyclase in target cells. It may also affect the ovaries in women and the testes in men
Calcitonin secreted by parafollicular cells of the thyroid gland
Parafollicular cells, also called C cells, are neuroendocrine cells in the thyroid. The primary function of these cells is to secrete calcitonin. They are located adjacent to the thyroid follicles and reside in the connective tissue. These cells are large and have a pale stain compared with the follicular cells.
*** SO OSTEOPOROSIS COULD BE TOO MUCH THYROCALCITONIN**
ALTERNATE SPLICING (SPLICED FROM A MAGNESIUM PATHWAY?)
Calcitonin also has significantly impacted molecular biology, as the gene encoding calcitonin was the first gene discovered in mammalian cells to be alternatively spliced, now known to be a ubiquitous mechanism in eukaryotes.
Calcitonin has clinically been used for metabolic bone disorders for more than 50 years.
MAGNESIUM HORMONAL REGULATION
Clinical and experimental data demonstrate that hormonal factors are involved in magnesium regulation. It is possible that the parathyroid hormone could play an important role in the maintenance of normal calcium and magnesium concentrations. The action of other hormones in magnesium metabolism appears to be an indirect response to factors such as calcium concentration or changes in volume. Alterations of the magnesium concentrations are important for the intracellular potassium, sodium and calcium content. Magnesium deficiency appears to lower intracellular potassium and to increase intracellular sodium and calcium concentrations. Therefore, magnesium is essential to avoid cardiovascular diseases (acute myocardial infarction, arrhythmias, hypertension) and to restore cellular potassium concentrations.
MAGNESIUM WHEN LOW MESSES UP POTASSIUM (lower) SODIUM (higher) & calcium & HEART
“Magnesium deficiency appears to lower intracellular potassium and to increase intracellular sodium and calcium concentrations. Therefore, magnesium is essential to avoid cardiovascular diseases (acute myocardial infarction, arrhythmias, hypertension) and to restore cellular potassium concentrations.”
MAGNESIUM REGULATION OLD SCHOOL INFO 1985
Magnesium: metabolism and hormonal regulation in different species
1. The magnesium ion is of great importance in physiology by its intervention in 300 enzymatic systems, its membrane role and its function in neuromuscular excitability.
2. The skeleton is the first pool of magnesium in the animal body.
3. For intestinal absorption, renal metabolism, bone accretion and résorption, magnesium shows analogies with calcium.
4. Magnesium exchange between extracellular, cellular and skeletal compartments are very precisely controlled.
5. Parathyroid hormone, 1α,25-dihydroxy-vitamin D3. calcitonin and estrogens are the principal hormone systems implicated in magnesium metabolism.
6. The kidney is the principal site of magnesium excretion and shows important magnesium regulation mechanisms.
MAGNESIUM USEFUL FOR MENSTRUAL CYCLE PROBLEMS
***Magnesium involved with menstrual cycle**
“magnesium as one of my favorite natural treatments for period problems.” Dr. Lara Briden
MAGNESIUM & HOT FLASHES
Magnesium can ease symptoms of the menopause transition (1). For example, in one study, magnesium relieved the menopausal hot flashes of women who were undergoing treatment for breast cancer and could not take hormone replacement (11).
MAGNESIUM CAN REDUCE STRESS
Magnesium calms the nervous system and reduces the activity of the hypothalamic-pituitary-adrenal (HPA) axis (2). The result is less anxiety, less cortisol, and a better capacity to cope with stress. Reduced stress can, in turn, have positive effects on your menstrual cycle and health.
If magnesium does help insulin resistance, then it could be a useful supplement for many of the long-term negative health consequences associated with insulin resistance, including the female endocrine disorder polycystic ovarian syndrome (PCOS), which is associated with insulin resistance. The benefits of magnesium for people with PCOS was demonstrated in one study where magnesium-zinc-calcium-vitamin D co-supplementation improved the insulin metabolism of 30 PCOS patients over 12 weeks (5).
MAGNESIUM & VITAMIN B6
Tip: Magnesium works best in combination with vitamin B6 (7)
Tip: Magnesium can also be used to prevent premenstrual migraines (1)
MAGNESIUM & ESTROGEN
Magnesium promotes healthy estrogen clearance.
By supporting the COMT enzyme (catechol-o-methyltransferase) in the liver, magnesium promotes the healthy excretion of estrogen (9). This may reduce the risk of the estrogen excess conditions (such as fibroids) associated with low COMT function (10).
2/3 AMERICANS MAGNESIUM DEFICIENT? Is that for real? Skeptical but need to investigate.
Magnesium deficiency is common and approximately two thirds of Americans have been found to not consume enough magnesium (12). One way to know if you might be deficient in magnesium is to try taking a supplement and see how you feel. Unless you have chronic kidney disease, magnesium is safe to try and safe for long-term use. Some forms (such as magnesium chloride) cause diarrhea, but gentler forms (such as magnesium glycinate) are usually fine.
*** I like this advice, if you think you might be magnesium deficient just take some and see how you feel! Good idea. Surely 2/3 of people are aren’t deficient but if they are they easy for them to do the feels test. ***
DRBRIDEN NATUROPATHIC DOCTOR RECOMMENDATION:
The best type of magnesium supplement is magnesium glycinate or bisglycinate (which is the mineral joined to the amino acid glycine). It’s the type that is most absorbable and is also the least likely to cause diarrhea. Magnesium bisglycinate has the added benefit of glycine, which calms the nervous system and improves insulin sensitivity (14,15).
MAGNESIUM DEFICIENCY & DEPRESSION
A magnesium deficiency has been linked to depression. It’s thought magnesium helps maintain the neurotransmitters in our brain related to moods. American researchers discovered that when people were given 125-300 mg of magnesium with each meal and at bedtime, they recovered from major depression in less than seven days.
MAGNESIUM CIRCADIAN RHYTHM
Research has shown that magnesium helps control how our cells manage the cycle of day and night. Keeping our body clock, or circadian rhythm, steady benefits sleeping, waking, hormone release, body temperature and other bodily functions. A study by the University of Edinburgh in 2016 found that magnesium levels in cells rise and fall through the day, regulating our body clock, but also affecting how well nutrients are converted into energy. The team say the discovery could help the development of chronotherapy, targeting medical treatments to specific times of day.
MAGNESIUM & SLEEP
Nearly 50% of older adults suffer from insomnia, but an Iranian trial discovered that magnesium supplements could help. Elderly people taking magnesium for eight weeks had ‘statistically significant increases’ in sleep time, sleep efficiency, and concentration of sleep-regulating hormone melatonin. They also scored lower on the Insomnia Severity Index, plus the length of time it took them to drop off dropped, as did their stress hormones.
MAGNESIUM PATHWAYS OLDER THAN ZINC PATHWAY?
Although there are only 1/10 as many magnesium enzymes in the body as zinc ones, the magnesium pathways seems older and even more mission critical to the body if you can believe that because of the importance of magnesium in stabilizing then body’s energy molecule ATP (adenosine triphosphate) and as a signaling molecule for low energy when magnesium ions are released. Because of high abundance of magnesium in sea water, and extremely early need in biological evolution for ATP energy (billions of years ago from the very beginning). Zinc meditation:
MAGNESIUM & IRON PATHWAYS
Magnesium seems to me to be as important as iron in creating the biological firestone of life & magnesium is mission critical for RNA & DNA development especially in adenosine pathways. I first thought about magnesium when meditating on iron:
MAGNESIUM REQUIRED FOR ANTIOXIDANT GLUTATHIONE
Magnesium contributes to the structural development of bone and is required for the synthesis of DNA, RNA, and the antioxidant glutathione.