Marsupials & Ticks

Because this is a Part 2, be sure to read Part 1 first if you missed it which is archived at imeddo.club/news   Enjoy!

For the tech focus of this episode, I interviewed Australian Brendan Lee of the Singapore based Faia Corp.  I’ve hired Faia consulting to revamp the imeddo.com website by end of summer to be hosted on the BitCoin Satoshi’s Vision (BSV) blockchain and to be BitCoin Metanet ready. However, because this episode got a little long, I’m going to push the bulk of Brenden’s interview to next month’s newsletter but include the part of his interview about ticks as is on topic.  Interview is located after tech update section near the end where I also give my final summary thoughts.

Welcome new iMedDo Distributor Dr. Candice Koch DC of Active Chiropractic Wellness Center from Colorado Springs. Congratulations! You can find Dr. Candice’s contact info at end in the Distributor Spotlight section.

MARSUPIALS & TICKS

by DrBenGo the Healthwarrior

Last month in July’s edition I wrote about Ticks & Lyme and my hypothesis that there is an undiscovered paralysis VENOM in ticks that needs more scientific and medical attention to be detoxed. Subsequent to publishing last month’s edition, I found quite a bit of information corroborating my hypothesis from scientists from the other side of the globe from the land down under AUSTRALIA!

WHY AUSTRALIA?

It turns out that the Americas & Australia have something in common: ticks & marsupials.  

In America we have hard ticks (Ixodes family) and in Australia they do too, the most notable of which is called Ixodes Holocyclus the Australian “Paralysis Tick”.

There are 3 types of mammals in the world: Monotreme, Marsupial & Placental. Of these types and oddity is that the only living marsupials are found only in the America’s & Australia.  We only have 1 species of Marsupial in N. America (Opossum) whereas Australia has hundreds (Kangaroos & Koalas & Many More).  My favorite is the now extinct Tasmanian tiger marsupial that kinda looked like a dog.

Marsupium is Latin for pouch, and a marsupial is a type of mammal with a pouch for its young.  Monotremes are egg laying and Placental like humans have internal eggs.  All mammals feed their young with milk.

It turns out that an American Opossum as a marsupial actually has quite a bit in common in it’s reproductive system with a kangaroo on the other side of the world & an annoying tick on my mountain (I’ve got lone star ticks & deer ticks) have a heck of a lot in common with a tick from the other side of the world in Australia!  

Now you might be thinking, that’s crazy how can that be possible. Just look at a globe, Australia and N. America are nowhere near each other, and I mean really nowhere near each other. I could literally more easily get to China than to Australia in 14 hrs to Beijing instead of a 19hrs flight to Sidney!  

Because we only have one marsupial in N. Americas the Possum (the ones in S. America looks like a furry mouse), and because there are so many in Australia, you might think that marsupials SOMEHOW came from Australia to the America but instead scientist now have evidence & reason to believe that opposite that the marsupials came from America (S. America to be specific).

Some of the stuff I’m about to tell you is gonna sound crazy and unbelievable, so I’m going to include a lot of references for those of you who want to dig deeper.  

My thesis for this article is that both ticks and marsupials migrated & evolved together, that the ticks & marsupials in North America are actually more similar than different to the ticks & marsupials in Australia. Although I don’t know much about the venom of American ticks, I found and now know a lot about the venom of Australian ticks.  Although I don’t know a lot about the marsupials in Australia, I know a lot about the one big fat marsupial who went through my trash last night the Possum here in America.  Putting it all together, I have found some very interesting insights into Ticks disease that I want my readers to know about.  

ABSTRACT

In summary for those of you who don’t have time to read this full article, what you need to know is that the Australian tick DOES in fact have a venom so there is no reason to think the American ticks don’t have a similar venom as well.  The venom is known to cause paralysis at the neuromuscular junction the area between the nerves and the muscle causing paralysis. The mechanism of paralysis has a similar endpoint as Botulinum Toxin (Botox) in that it results in less Acetylcholine released by the presynaptic neuron and results in less downstream contraction in the muscle.  However, the way the tick venom works is not by inhibiting ACH vesicle release as in Botox but instead the tick venom monkeys with the CALCIUM levels in the synaptic cleft reducing it or making the voltage gated calcium channels less responsive to the calcium signal ultimately resulting in less Acetylcholine being released from the presynaptic neuron and thus downstream paralysis.  I talk a lot about marsupial and tick evolution and continental drift theory and ultimately I relate how I think the Opossum has special adaptation against tick venom and lyme which we can learn from.  
The most novel observational thought I had from this line of thinking is that CALCIUM SUPPLEMENTATION could be of benefit for those suffering from Lyme & that one of the reason detoxing with iMedDo System is likely reported beneficial for those with Lyme (not that I can sell it for that only as a health supplement not a drug) is because it detoxes the halogens which also have a similar negative effect on calcium signaling. I’ve covered such topics as how fluoride halogen can bind and also disrupt calcium signaling in previous newsletters such as “Halogen talk” and about kidney & adrenal regulation of calcium using a complex pathway disrupted by fluoride in “Fluoride & Kidney Stones” prior newsletter which are worth going back and reading if you missed them: news.imeddo.club for archived newsletters.

For those of you who want to delve deeper into reviewed data and see where I came up with this crazy line of tick & marsupial thinking keep on reading!    


THE ANTARCTIC MARCH OF THE MARSUPIALS & THEIR TICKS FROM AMERICA TO AUSTRALIA

Although continents of the Americas & Australia are separated by millions of years, there is one thing we have in common: marsupials & ticks.  In America our marsupial is the opossum whereas in Australia they have many more marsupial species (most famous is the kangaroo).

https://www.wideopenspaces.com/know-opossums-eat-virtually-ticks-yard/

Although all marsupials in the Americas are extinct except opossums, there are actually a lot of fossil data of marsupials in S. America.  

All marsupials are originally from South America.
Source: https://www.livescience.com/6770-marsupials.html

However, for this to be true the missing key is called continental drift theory which explains that all of the earth’s continents at one time in the distant past were connected. Indeed several such super continents have been proposed by geologists including Pangea and Gondwana.   

See pic of Gondwana centered at South Pole.  
https://en.wikipedia.org/wiki/Gondwana#/media/File:Gondwana_420_Ma.png
 

There was a time where S. America was connected to Australia via the land bridge of by the continent of Antarctica! You know, that really big ice cycle continent near the South pole home of all good conspiracy theories.

Possums in N. America didn’t have far to go if marsupials originated in S. America but that Marsupials in Australia living today like the Kangaroo must have ancestors who cross continent hiked millions of years ago.  Although on opposite sides of the world now the Opossum and Kangaroo share distant S. American relatives!

If you look at the graphic at the start of this newsletter you can see that S. America, Antarctic and Australia were all connected 65 million years ago in what is called the Cretaceous period allowing this link and no doubt ticks were there along with them maybe hiking on their backs =) Unlike marsupials however ticks are found everywhere across the world but these isolated ticks & marsupials may have developed and co-evolved together.  

To give you an idea of time, ~300 million years ago was when my grey limestone here at the base of Appalachians was formed.  ~100 million years ago was when the white limestone in Texas was formed.

Although Antarctica and Australia were connected all the way from ~50-300 million years ago, It was probably more like ~50-75 million years ago not 150-300 million years ago that marsupials or marsupial ancestors (monotremes) may have migrated from S. America through Antarctica to Australia.

If that’s true then surely there are some marsupial fossils to be found in Antarctica?

Sure enough marsupials fossils have been found in Antarctica about 40 million years old and similar to fossils from that time found in S. America.

Source: https://www.nytimes.com/1982/03/21/us/antarctica-yields-first-land-mammal-fossil.html

Okay, fine if I believe that American marsupials marched across Gondwanaland through what is now Antarctica and into Australia then what about the ticks?

The origins of ticks have been estimated to in the late Cretaceous, ~120 million years ago, which was the last time that Australia was part of Gondwanaland, indicating the this period played an important role in the origin of the Australian tick lineages, and by extension, the entire tick family.  

Source: Klompen et al. 1996, 2000.  

This dating of tick evolution as blood sucking spiders (previously insect eating spiders) to 120 million years ago is very interesting. They are a type of Arachnid as are scorpions.   

I’m imagining a time from about 120 million years ago to 50 million years ago when ticks and pre-marsupial to marsupial mammals were all stuck on a big island together (post Australia being a part of Gondwanaland but before Australia broke off from Antarctica)

Concerning ticks though the oldest tick fossils found thus far are approximately 100 million years old trapped in amber from tree sap while trapped in spider silk.  

History, suspects that a spider intercepted the tick as it tried to feed on tree-climbing raptor dinosaurs.

Source: https://www.nationalgeographic.com/news/2018/05/fossils-ticks-spiders-dinosaurs-amber-cretaceous-science/  

The irony is that as ticks evolved from spiders to eat the blood of reptiles & birds  instead of other insects, there were still spiders around to eat them.  

At some point maybe 100-50 million years ago (75 million  years ago?) the reptile-bird family evolved into the first mammals which were known as monotremes which preceded the marsupials & placental mammals.  The monotremes are egg laying mammals an the only ones living today are in Australia and New Guinea (near Australia) the platypus and the echidna.  

Keep in mind that around that time 65 million years ago: Cretaceous S. America, Antarctica & Australia were all still connected!
Source: Pic https://en.wikipedia.org/wiki/Pangaea#/media/File:Pangaea_to_present.gif

At some point the ticks learned to not only eat dinosaur/raptor/lizard blood but also to eat mammal first monotreme mammal and then marsupials in &/or placental mammals.

One theory is that Antarctica served as a biological filter keeping out the placental mammals only allowing the marsupial mammals from the Americas onboard, then later off boarding them in Australia 50-55 million years ago.  

Source: https://www.nytimes.com/1982/03/21/us/antarctica-yields-first-land-mammal-fossil.html
 
I suspect that the marsupial pouch may have been an advantage to keep the monotreme egg warm in a cold environment (Antarctica) during marsupial evolution and migration.

I also wonder if monotreme mammals evolving a pouch to early hatch their eggs and start nourishing them with antibacterial milk was in response to either and insect or bacterial egg rot they may have encountered. Could the tick or some other insect been the cause of this natural selection?  

Maybe the monotreme mammals hatching S. America-Antarctica-Australia were freezing to death, or were getting eaten before during or shortly after hatching on the ground either way being carried in a pouch and the evolution of the marsupial might be preferred.  

Once marsupials evolved to be the preferred form of mammal the baby “joeys” which have to fast hatch at early development and then crawl to the teat for milk would be highly susceptible to an insect that had a paralysis venom.

If bitten and paralyzed before making it to the teat the joey would die but serve a good snack for an unscrupulous insect like a paralysis tick.  

My hypothesis is that because a tick would represent a major threat to a marsupial mammals reproduction that it had to develop defenses against such attacks and furthermore, I suspect and postulate that we can see evidence of such defensed by observing our N. American Opossum.

By combining the tick paralysis venom information discovered by Australian scientists with the marsupial observations of the American Possum, I think we get a clearer picture of what may have happened sometime 100-50 million years ago when monotremes—> marsupials were stuck around Antarctica between S. America & Australia and had to co-evolve with ticks.

Ticks evolved into 3 families:

Ticks (suborder Ixodida) are obligate hematophagous [blood eating] organisms that comprise three families, the Ixodidae (hard ticks), Argasidae (soft ticks), and Nuttalliellidae (monotypic). Source: Hoogstraal 1956.  

Ticks don’t seem to have changed much in the last 100 million years, they look fairly similar and have 8 legs like spiders and are blood suckers and as discussed evolved the ability to eat blood instead of other insects circa 120 million years ago likely to eat dinosaurs lizard snakes and birds first then later to eat mammals first monotremes then marsupials & placentals.

I found some great Australian science which uses classical Neuroscience to elucidate the nature of the paralysis tick venom from the most paralyzing of all Australian ticks the Ixodes holocyclus.

When you think about a paralysis venom on top of any infectious agents in the American tick bite then many of the Lyme disease symptoms start to make a lot more sense.  I do think there can be a bacterial and/or virus and/or saliva immunomodulating component but additionally there is a VENOM component that has previously been mostly ignored in N. Amercian ticks but which they cannot ignore in the Australian paralysis ticks.

Because the tick mostly lives on the eastern Australian seaboard where most of Australia’s human population lives and because the tick frequently both encounters humans, pets & livestock frequently even killing the pets & livestock there appears to have been more Australian science directed at studying ticks than in North America.

Ticks are of interest to veterinary science with impetus that the ticks are killing pet dogs & cats (small animals) and livestock (large animals).
Ticks are of interest to Big Pharma as like mosquitos they can be vaccine vectors and the flip side is that they are also of military interest as bioweapon delivery system.

The tick paralysis venom is highly toxic and is of military significance of similar effect as Botulinum toxin (Botox) which has documented military significance in the US, so don’t mess with the Australian military as they very likely have a tick venom espionage weapon.  The mainstream (pharmaceutical-drug-vaccine i.e. Big Pharma) interest in tick venom is to develop a “tick vaccine”.  Because the payoff in mainstream medicine is very high if you can patent a drug, a lot of money in Australian science has been thrown at the tick problem and I found quite a bit of research has already been done.  Not only do they know the structure of the paralysis venom but they know the mechanism, and they even have a patent on the toxin so likely they are working feverishly on trying to make a tick vaccine which is the endpoint for most mainstream medicine though not necessarily the best endpoint for human health.  They may not have much luck in their clinical trials since vaccine aluminum like tick venom also suppresses the nervous system but unfortunately oftentimes the hippocratic oath to do no harm takes a back seat to dollar bills in mainstream veterinary & human medicine which is focused on drugs and vaccines.   

Tick research is a hot area. According to wikipedia search “Tick-borne disease”  As of 2016, 16 tick-borne diseases of humans are known (four discovered since 2013).

The hottest research of all is this 2016 Neuroscience study showing that the tick venom is similar in downstream effect as the Botulinum toxin (inhibits presynaptic Acetylcholine release across Neuromuscular Junction resulting in paralysis).

The study convincingly shows that the tick venom somehow reduces the effective amount of calcium in the synaptic cleft possibly by blocking voltage gated calcium channels or by binding calcium directly.

Chand, K. K. et al. Tick holocyclotoxins trigger host paralysis by presynaptic inhibition. Sci. Rep. 6, 29446; doi: 10.1038/srep29446 (2016).

Source Link: https://www.nature.com/articles/srep29446

After reading the paper, my thoughts are that since the tick venom reduces available calcium that anything that also reduces available calcium like fluoride (binds as insoluble calcium fluoride) would be synergistically toxic, one reason why detox is important.

I want to stop here and just mention a major difference between mainstream and alternative medicine.  In mainstream medicine it focuses on veterinary medicine as animal (mice) models are used in drug & vaccine development.  They seek a patent & $$$.  Additionally funding is for military usages of strong venoms and the strongest naturally occurring tick paralysis venom is found in the Australian tick. There for Australian tick research would be top priority in mainstream medicine.  In alternative medicine or at least my flavor of alternative medicine, I focus on humans not animals but as a biochemist/biologist/biophysicist/neuroscientist trained biologist, because of the similarities of all lifeforms (we all use DNA for instance) I also think about animals though am not a veterinarian.  But I’m not thinking about research for the sake of a patent to make a paralysis drug or an anti-paralysis vaccine, but am instead thinking about it for the sake of what is best for humans to understand the issue from a natural perspective to look for natural and nutrition solutions.  It’s really just a difference of intention.  My intention is to heal not kill.  My intention is to nourish not poison.  You can look at the same information and see different things if you are thinking about it from a different intention.

When I look I see poisons in the water and in the food and in the vaccines which synergistically make tick poison worse.   What is the difference between most people who get bitten by a tick and are mostly fine maybe a little gut issues vs. the ones who develop a terrible mammalian meat allergy? Could it just be the amount of cumulative toxins in their body?

Many of the “medical” uses of Botox & thus tick venom are unethical in my person opinion.  People think it is medicine inject a toxin for cosmetic usage only to find it spreads and harms other parts of their body.  Using toxins to heal is of no interest to me compared to detoxing toxins to heal.

My hypothesis that the American ticks should have a paralysis venom is spot on highly likely based on the Australian research presented above (Chand 2016).

If the Australian ticks have a known paralysis venom and the science has been done which it has then this can be used for a major advancement for the American scientists to use to know where to look and what to look for when studying the North American tick varieties.

Keep in mind that there are many species of ticks all over the world and just like many species of spiders or scorpions their venom may be slightly different BUT there should be some similarities in function and by looking at the function of one it should give you an idea about the possible and potential function of the other in the absence of data.  

So my main hypothesis is that although the paralysis venom from the Australian tick may not be exactly the same as the UNKNOWN paralysis venom in the American tick species that it could very well be SIMILAR in function.  

Until the science is done on the American ticks we can learn a lot from and ASSUME that something similar is going on as in the Australian ticks.

The American paralysis venom appears to be weaker as when you remove the tick the paralysis usually dissipates in a few hours, the Australian tick when removed the person or animal can actually get WORSE for the next few days before getting better.  

In both cases the VENOM appears to be coming from the tick’s salivary glands.  The venom is a PROTEIN venom.   A protein is composed of amino acids which are encoded by RNA by DNA in all life.  

Although the protein sequence and function of the American ticks is not known to me, I found detailed data on the Australian tick (Ixodes holocyclus) protein venom.  

It is a protein of about 40kDa in size but is also a family of proteins maybe one 5kDa in size and 80kDa in size as well and they likely work together for toxic effect.  (Proteins are measured in kDa (kiloDaltons) unit of weight which correspond to very small nanometer sizes where size if you simplify as a sphere depends on how the protein is folded)     

Not only have the Australians sequenced the exact amino acid composition of the 40kDa protein venom they have also patented it which is necessary for drug/vaccine/&military artificial synthesis of the venom.  

Additionally the Australians have done a very good bit of Neuroscience (I really like this study) where they compared the effect of salivary extracted venom to the artificially sequenced venom on the neuromuscular junction where nerves meat muscle and paralysis happens.  

What is the effect?

Quite simply the TICK VENOM is monkeying with the CALCIUM levels in the neuromuscular junction (NMJ).  It is clear the venom is somehow making the nerve less responsive to calcium signaling.  

The Neuromuscular junction just like it sounds is where a nerve connects with muscle tissue.  There is a slight gap (synapse) where levels of chemicals in the gap signal to the nerve (pre-synaptic side) to release chemical signals into the gap which are received by the muscle cell (post-synaptic side) which tell the muscle to contract.  

The ability to study the NMJ is a major accomplishment of mainstream Neuroscience in which I am classically trained.

What is known is the signaling molecule (neurotransmitter) that the presynaptic neuron releases is called Acetylcholine (ACH).  If the for some reason less ACH is released then there will be less muscle contraction.  

The tick venom is indirectly blocking the release of ACH into the synapse resulting in up to about 50% less muscle responsiveness which explains a large part of the TICK PARALYSIS (unresponsive muscles) seen with a tick bite from the Australian tick (Ixodes holocyclus).

Different known paralysis toxins can block the ACH pathway by different mechanisms but the experiment conclusively demonstrates that what is happening is that the tick venom is blocking the ability of the presynaptic neuron to respond to CALCIUM signals.  

It is required that the presynaptic neuron allow into itself through voltage gated calcium channels the ionic calcium (Ca2+) as an upstream signal to it releasing ACH by fusion of vesicles full of ACH to its membrane to dump the ACH into the synapse between the neuron & the muscle which is the signal for the muscle to contract.

Compare the Tick paralysis venom to Botulinum Toxin (Botox) which has the same end result (Less ACH and therefore less muscle contraction i.e. paralysis). However the mechanism is different whereas the tick venom block calcium signal to presynaptic cell to release ACH, Botox blocks the binding of the ACH vesicle from leaving the presynaptic neuron however in both cases you end up with not enough ACH in the synaptic cleft and therefor not enough muscle contraction (paralysis).  

The reason that paralysis can be very fatal (deadly) in mammals is that for us to live we need our diaphragm muscle to be constantly working as it is required for our lungs to open and close for us to breath.  

So it’s not the paralysis of all your muscles that kills you but the one muscle in particular the diaphragm muscle underneath your lungs whose contraction and release creates the pressure difference required for you to cycle air into and out of your lungs for respiration.   If the diaphragm is paralyzed even for only a few minutes you die of lack of air (Asphyxiation) and likely the paralysis venom of the tick works in a similar way on small animals such as rodents and baby (joey) marsupials in the wild which include Opossums in North American and Kangaroos in Australia.  

Few humans die of ticks in N. America but a number of human fatalities mostly children have been reported in Australia.  However, I wonder how many humans are suffering from long term tick bite venom effects in N. America which are not reported.  Even some people who test negative for Lyme bacteria could still be affected by the paralysis venom.

Hopefully thinking about marsupial and tick co-evolution will give additional insight in ways mammals can try to cope with ticks.

The evolution of a pouch to protect the external egg was a great development monotreme-marsupial.  However, one unforeseen problem was that now having an external small joey that had to crawl after hatching from point A to B to get to the teat is defenseless agains paralysis ticks.  

I suspect that ticks learned to crawl on the parent marsupial and try to bite and paralyze the joey which would not make it from hatching to teat.  This could be terrible for the parent marsupial because now the pouch adaptation which protected the egg has now become a pocket for a tick infestation.  

If my hypothesis is correct then marsupials are at a reproductive disadvantage in the presence of ticks and to survive would need to develop specific adaptations to survive and to increase their chance of viable offspring.  

LESSONS FROM THE OPOSSUM

Looking at the American Possum it appears these adaptations are in place.  

The Possum has learned to eat 90%+ of ticks it encounters and can eat 5000 ticks in a season. The adaptation to clean itself of ticks was likely a critical adaptation for N. America’s only surviving marsupial to continue surviving.

Even thought the adult possum can voraciously eat ticks and thus protect itself, the young joeys of a marsupial would be a different story.  

A Possum has increased its number of young that hatch and crawl in the pouch.  With 13+ making their way to the teat and others perhaps getting paralyzed by ticks from the 10% of ticks the parent possum missed.

Just as a vaccine is dangerous because it bypasses your natural defense systems in your gut, a tick bite injection directly into your blood is the same.  But if you ate a tick directly like a possum, it would allow the toxins to go through your defense system in a way that your body could hopefully recognize and mount a proper immune response against.  Immunology is not my strong suit but know that a lot of immunology research on ticks has been done and a number of immunomodulators in tick saliva have also been found which help the tick bite you without you noticing.  It wants to suppress your immune system so the bite doesn’t get inflamed until it first gets enough to eat then falls off first (then it doesn’t care if you get a rash afterwards).

So I have to wonder if it would be beneficial for humans to eat ticks.  I don’t know and I’m not gonna try this but I do think that someone should research this.  If a marsupial possum does it might also be beneficial for us.

Secondly I have to wonder if it would be beneficial for us to eat a possum. In last issue I said emphatically “Don’t try to eat possum!” but since then I have learned that many have successfully eaten possum, they key is removing their gland first otherwise they taste diseased.  Does eating possum give any immunity to ticks? Inquiring minds want to know but also I’m not recommending that and I’m not gonna try it =) Possum Yuck! Though I have read they supposedly taste like pig.

Possums have a trick called “Playing Possum” where they act dead.  They do a very convincing job where they bare their teeth & salivate and also release a substance from their anal gland that makes them smell diseased.

I have to wonder if the Possum evolved this trick as part of it’s co-evolution with tick paralysis venom.  Imagine a possum partially paralyzed who for some reason got a competitive advantage in the wild as some predator would leave it alone if it thought it was already dead.  This is a fascinating line of thought and for the intrepid scientist I would recommend analyzing the possum saliva and gland secretions for any evidence that the possum uses the tick paralysis venom as part of its own ploy!  I suspect as a voracious tick eater it might actually be storing and using the venom for its own protection after evolving to become immune to it.

Possibly the most instructive observation of the Opossum, the marsupial who has evolved to live with ticks on its trek from S. America or possibly even all the way across Antarctica to Australia and back in its genetic history is its weird dietary intake of CALCIUM.

Opossums have big strong jaws and teeth and crunch rodents bone in.  They love bones and have a seemingly high calcium intake for their size.
Now that we know the tick venom is suppressing calcium, we have wonder if the possum is compensating for the tick venom effects by having a high calcium diet? And more importantly WOULD IT BE BENEFICIAL FOR HUMANS SUFFERING FROM TICK BITE DISEASES OR TOXIN TO ALSO INCREASE THE CALCIUM IN THEIR DIET?  I think it just might and that is an easy thing for people do and try, would love to hear feedback on that.  Unlike the other two things, eating ticks or eating possum meat, trying a calcium supplement (for me my calcium supplement of choice is goat or cow milk) is something I can get behind.  
I suspect that many who have been bitten by ticks have an underlying CALCIUM DEFICIENCY which can be exacerbated by all sorts of environmental toxins and even iodine nutrient deficiency.  Calcium is used everywhere in the body and anything like tick venom or fluoride that suppresses it is a problem, anything that suppresses your kidneys is a problem, vitamin D, sunlight, magnesium deficiencies are a problem, etc.

IN CONSLUSION:

Thinking deeply about ticks and marsupials in N. America and Australia and their evolution and examining Australian science on tick venom and thinking about the N. American Opossum as a marsupial who has evolved to defend against ticks and their venom, I think that my hypothesis that ticks in N. America have an undiscovered venom is justified.  Until we have more info we can assume it is similar to the Ixodes holocyclus venom in Australia though of a weaker variety.  Whereas the venom has maximum effect several days after ticks removed in Australia, perhaps the venom has maximum effect weeks, months or even years after tick is removed in America.  If so this “weakened venom” or “persistent late acting venom” could explain many of the unknown effects of “Lyme” disease in America which is poorly understood and seems more of a toxin problem than just a bacterial problem to me.  
TECH UPDATE

DrBenGo hired Faia Consulting to make imeddo.com Metanet ready and the interview with Brendan Lee is being pushed to next month’s episode to explain to us what that means.  For now I’m excited because Brendan got my old email healthwarrior@imeddo.com up and working again! It now forwards to abengoins@gmail.com.  While imeddo.com is still down for maintenance you  can type in www.imeddo.com it will redirect to www.imeddo.club the fan site in the meantime . For ordering use Etsy shop at imeddo.club/buy or for distributor orders email me directly or call me for questions, ordering, or spiritual advice.

INTERVIEW WITH AUSSIE BRENDAN LEE ON TICKS

DrBenGo: As an Australian Brendan, tell us about your experience with Australian ticks? 

Brendan Lee: Australia has a lot of ticks, and a wide zone where tick bites have inexplicably begun giving people meat allergies. I live almost in the center of this zone and I and other members of my family have had ticks before. Thankfully we watched this:

and were able to perform the proper removal rather than the far more dangerous (and common) tweezer pull. In the local bush we have several types of ticks, one of which is a paralysis tick. One of these onto our family dog and we didn’t find it until it was the size of a grape. Sadly he was weak from a recent snake bite (he was an adventurous sort) and died a few days later. Vale Buck!

Dr. BenGo:  Thankyou so much for sharing that Brendan.  It has some valuable information that I want me readers to know and our condolences on losing your dog to the paralysis tick (Ixodes holocyclus) whose venom I discuss in this episode.

FINAL COMMENTS BY DRBENGO ON TICKS

The ticks of N. America are actually quite similar to the scary Ixodes Holocyclus paralysis tick of Australia because of the Marsupial land bridge connection.  The two main types of ticks I have in my yard are the lone star tick and the deer tick with predominantly the lone star tick.  Most of the time, I feel the tick crawling on me, and am able to safely remove it with a tweezer BEFORE it bites. The  crawling lone star tick feels like a drop of water on the skin, and if I feel what feels like a bead of sweat I always tick check .  However, if you find a tick that has already bitten you, thanks to Brendan and the Australia recommendations for tick removal in the video he shared in his interview question above, I think that is something Americans should try:  FREEZE NOT SQEEZE the tick! By doing that way it will result in less tick saliva & venom and blood squirted back into the wound.  We know know thanks to Australian science that the N. American meat allergy to deer is most likely the same as the mammalian meat allergy that the Australians discovered which is caused by the prior animal the tick was munching on. So if you get bit by a tick that previously ate a deer than if it bites you next and injects enough blood then you can develop a DEER MEAT allergy. For N. American readers, I recommend that deer hunters be extremely careful to avoid ticks from deer prey from crawling onto them while dressing the deer.  These ticks have eaten deer recently, and if bite a human can give deer meat allergy in some people.  The most interesting comment I have is that since the tick venom hinders calcium in the neurons causing paralysis and combined with the observation that Opossums eat high calcium diets that anything which helps calcium processing such as iMedDo detox system, calcium supplementation or milk (high in calcium) could potentially help negate the effects of tick venom and that anything that hinders calcium signaling such as fluoride which insolubly binds with calcium or aluminum from vaccine vaccinosis which makes more fluoride soluble into the brain (aluminum-fluoride) would make tick venom and tick diseases from bacteria & virus worse (such as Lyme) or from immuno-inflammation worse (such as meat allergy). 
I think that tick bite problems are only going to get worse & worse in both America & Australia because I believe they are exacerbated by vaccinosis which is a topic and a correlation that mainstream medicine does not want to admit.  My philosophy is to be in a constant state of detox and when you get poisoned you will be able to deal with it much easier than if you are already full of toxins.  Like Brenden’s poor dog who just couldn’t take both snake venom and then tick venom on top of it, many Humans may not be able to take both vaccine toxin with tick venom on top.  As we see both tick and vaccine allergies rise note that tick paralysis is frequently misdiagnosed as Guillane-Barre paralysis  from vaccinosis and vice versa.  The two are related as they both suppress the nervous system.

BITCOIN DISCLAIMER: NOT FINANCIAL ADVICE DO YOUR OWN RESEARCH INVESTING IS RISKY NEVER INVEST MORE THAN YOU CAN AFFORD TO LOSE. 

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